Summary

  • In 2010, a $2.6M grant was awarded to R&D by the NIH funding the pivotal clinical study to obtain FDA marketing clearance.
  • In 2018, the results of our early clinical studies were published in the Journal of Applied Laboratory Medicine and demonstrate that our PliNOSa┬« test data strongly supports extracellular plasma iNOS in circulating microvesicles is centrally involved in the initiation of sepsis, and show that a diagnostic test based on plasma iNOS can serve as an early pre-symptomatic warning signal for the onset of sepsis. View the clinical study results.
  • In December 2021, the results of animal studies for our sepsis monoclonal antibody immunotherapeutic were published in the International Journal of Molecular Science, in their special issue focused on sepsis. View the animal study results.